Seminar Talks

Department of Physics, UC Davis (May, 09)

Pattern Formation of Membrane-Bound Molecules Underlies Biological Molecular Recognition

Department of Mathematics, UC Davis (March, 08)

Simplified models of receptor-ligand binding and intracellular signaling

Center for Comparative Medicine, UC Davis (February, 07)

Computational modeling of B cell signaling

Department of Physics, Jadavpur Univeristy, Kolkata, India (December, 06)

Cell death decision: deterministic or stochastic?

Department of Biology, University of Texas, San Antonio (May, 06)

B cell immunological synapse: a macromolecular assembly for antigen recognition

Meeting presentations (Oral)

1. Biomedical Engineering Society Meeting 2010

Bcl-2 and XIAP inhibit apoptosis by modulating intrinsic variations in the mitochondrial pathway

2. 10th UC Wide Bioengineering Symposium 2009

Energy based Monte Carlo simulation of B-cell receptor clustering

(Presented by A. Srinivas Reddy)

3. 10th UC Wide Bioengineering Symposium 2009

Computational modeling of immunological synapse formation shows that cytoskeletal transport of receptor molecules is a potential formation mechanism

(Presented by Philippos K. Tsourkas)

4. Biomedical Engineering Society Meeting 2008

B cell immunological synapse modulates response to antigens of varying affinity

5. Biomedical Engineering Society Meeting 2008

A minimal model of signaling network showing stochastic effects

6. Biomedical Engineering Society Meeting 2008

A Probability distribution based approach to analyze cell-to-cell stochastic fluctuations in    cell death signaling and diseases

7. Biomedical Engineering Society Meeting 2007

Monte Carlo simulation of immunological synapse formation in B cells

(Presented by Philippos K. Tsourkas)

8. American Physical Society Meeting 2007

How cells decide between life and death: predictions from stochastic simulations

9. American Association of Immunologists Annual Meeting 2006

Molecular Dynamics of B cell synapse formation modeled in silico

10.  International Conference on Molecular Systems Biology, Tahoe City, 2004

An effective membrane model of the immunological synapse

11.  American Physical Society Meeting 2004

T Lymphocytes hunt for antigen in lymph nodes like lone sharks

Meeting presentations (Poster)

12.  American Association of Immunologists Annual Meeting 2010

Computational studies of B cell receptor diffusion elucidate mechanisms of B cell immune       synapse formation

13.  American Association of Immunologists Annual Meeting 2010

B cell affinity discrimination requires kinetic proofreading

14.  American Association of Immunologists Annual Meeting 2010

B cell receptors micro-cluster by antigen cross-linking and macro-cluster in a cap by biased transport

15.  Biomedical Engineering Society Meeting 2009

Stochastic fluctuations in apoptosis are linked to network design and apoptosis related diseases

16.  Biomedical Engineering Society Meeting 2009

Affinity discrimination in B cells is mediated by early signaling events

17.  American Association of Immunologists Annual Meeting 2009

Monte Carlo simulation of immunological synapse formation in B cells

18.  American Association of Immunologists Annual Meeting 2009

Monte Carlo model elucidates mechanisms of B cell affinity discrimination and its modulation by B cell immune synapse formation

19.  Biophysical Society Meeting 2009

Monte Carlo study of apoptosis: Stochasticity in cell death due to mitochondrial release step

20.  American Physical Society Meeting 2008

A minimal stochastic model of cell death signaling

21.  Biophysical Society Meeting 2008

Stochastic simulation reveals the mechanisms of immunological synapse formation in B cells

22.  Biophysical Society Meeting 2008

A Monte Carlo computational method for modeling of receptor-ligand binding-mediated processes

23.  Biophysical Society Meeting 2008

How cells decide between life and death: predictions from stochastic simulation

24.  American Physical Society Meeting 2008

A minimal stochastic model of cell death signaling

25.  American Association of Immunologists Annual Meeting 2007

Stochastic simulation of B cell signaling reveals affinity discrimination through B cell

synapse formation

26.  Biomedical Engineering Society Meeting 2007

Apoptotic Cell Signaling is Robustly Designed

27.  Biophysical Society Meeting 2007

How cells decide between life and death: predictions from stochastic simulation

28.  American Association of Immunologists Annual Meeting 2006

Molecular Dynamics of B cell synapse formation modeled in silico

Workshop

Imaging, Interpretation and Modeling in Modern Immunology (Banff, Canada, 2011).

Talk title: How B cells discriminate antigen affinity (over five orders of magnitude)