Leach Lab


Welcome

Human mesenchymal stem cells on biomineralized polymeric thin films (Rao, He, and Leach. J Biomed Mater Res (2010)).

Welcome to the Leach Laboratory at UC Davis!

Research in the Leach laboratory is primarily in the broad area of cellular and tissue engineering. Within our research program, we seek to engineer functional replacement and temporary bridge tissues while also developing model systems to study physiological and pathophysiological tissue formation. We initially develop many of our projects with an eye toward bone tissue engineering, and these findings are subsequently applied to other areas of tissue repair including cartilage, cardiovascular, and neural tissue engineering.

All projects in the lab are linked by the hypothesis that combinatorial approaches to tissue formation are superior to individual stimulation. More specifically, successful tissue engineering approaches will be realized upon the proper spatial and temporal presentation of cells, signaling molecules, biomaterials, and mechanical stimulation.