Publications
Selected Publications
Banyasz T, Horvath B, Jian Z, Izu LT, Chen-Izu Y. Profile of L-type Ca(2+) current and Na(+)/Ca(2+) exchange current during cardiac action potential in ventricular myocytes. Heart Rhythm. 9(1):134-42 (2012). Reprint.
Bányász T, Szentandrássy N, Tóth A, Nánási PP, Magyar J, Chen-Izu Y. Cardiac calmodulin kinase: a potential target for drug design. Curr Med Chem. 18(24):3707-13 (2011). Reprint.
Banyasz T, Horvath B, Jian Z, Izu LT, Chen-Izu Y. Sequential dissection of multiple ionic currents in single cardiac myocytes under action potential-clamp. J Mol Cell Cardiol. 50(3):578-81 (2011). Reprint.
Chen-Izu Y, Izu LT. Cellular cartography. Biophys J. 99(12):3861-2 (2010).
Chen-Izu Y. Multiple levels of the single L-type Ca2+ channel conductance in adult mammalian ventricular myocytes. Biochem Biophys Res Commun. 391(1):604-8 (2010). Reprint.
Banyasz, Tamas; Lozinskiy, Ilya; Payne, Charles; Edelmann, Stephanie; Norton, Byron; Chen, Biyi; Chen-Izu Y; Izu, Leighton; Balke, CW. Transformation of adult rat cardiac myocytes in primary culture. Experimental Biology 93(3):370-82 (2008). Reprint.
Chen-Izu, Ye, Ling Chen, Tamás Bányász, Stacey L. McCulle, Byron Norton, Steven M. Scharf, Anuj Agarwal, Abhijit Patwardham, Leighton T. Izu, C. William Balke. Hypertension-induced remodeling of cardiac excitation-contraction coupling in ventricular myocytes occurs prior to hypertrophy development. Am J Physiol. 293:H3301-3310 (2007). Reprint.
Izu, LT, Banyasz T, Balke CW and Ye Chen-Izu. Eavesdropping on the Social Lives of Ca2+ Sparks. Biophysical J 93:3408-3420 (2007). Reprint.
Chen-Izu, Ye, Chris W. Ward, Wayne Stark Jr., Tamas Banyasz, Marius P. Sumandea, C. William Balke, Leighton T. Izu. Xander H.T. Wehrens. Phosphorylation of RyR2 and shortening of RyR2 cluster spacing in spontaneously hypertensive rat with heart failure. Am J Physiol . 293(4):H2409-17 (2007). Reprint.
Banyasz, T, Chen-Izu, Y, Balke CW, Izu Leighton. A New Approach to the Detection and Classification of Ca2+ Sparks. Biophysical Journal 92:4458-4465 (2007) [Banyasz and Chen-Izu contributed equally]. Reprint.
Chen-Izu, Ye, Stacey L. McCulle, Chris W. Ward, Christian Soeller, Bryan M Allen, Cal Rabang, Mark B Cannell, C William Balke, Leighton T. Izu*. Three-dimensional Distribution of Ryanodine Receptor Clusters in Cardiac Myocytes. Biophysical Journal 91:1-13 (2006). Reprint.
Leighton T Izu, Shawn Means, John Shadid, Ye Chen-Izu, C. William Balke. Interplay of Ryanodine Receptor Distribution and Calcium Dynamics. Biophysical Journal 91:95-112 (2006). Reprint.
Kirk MM, Izu LT, Chen-Izu Y, McCulle SL, Wier WG, Balke CW, and Shorofsky SR*. Role of the transverse-axial tubule system in generating calcium sparks and calcium transients in rat atrial myocytes. Journal of Physiology 547(2):441-451 (2003). Reprint.
Chen-Izu Y, Moreno AP, Spangler RA. Opposing gates model for voltage gating of gap junction channels. American Journal of Physiology 281:C1604-C1613 (2001). Reprint.
Chen-Izu Y, Xiao R-P, Izu LT, Cheng H, Kuschul M, Spurgeon H, and Lakatta EG. Gi-dependent localization of b2-adrenergic receptor signaling to L-type Ca2+ channels. Biophysical Journal 79:2547-2556 (2000). Reprint.
Kuschel M, Zhou Y-Y, Cheng H, Chang S-J, Chen Y, Lakatta EG, and Xiao R-P. Gi protein-mediated functional compartmentalization of cardiac b2AR signaling. Journal of Biological Chemistry 274:22048-52 (1999). Reprint.
Sham JSK*, Song L-S, Chen Y, Deng L-H, Stern MD, Lakatta EG, and Cheng H. Termination of Ca2+ release by a local inactivation of ryanodine receptors in cardiac myocytes. Proceedings of National Academy of Sciences USA 95:15096-15101 (1998). Reprint.
Chen Y, Simasko SM, Niggel J, Sigurdson WJ, and Sachs F*. Ca2+ uptake in GH3 cells during hypotonic swelling: the sensory role of stretch-activated channels. American Journal of Physiology 270:C1790-C1798 (1996). Reprint.
