Publications
2013
Makris EA, Hu JC, Athanasiou KA. Hypoxia-induced collagen crosslinking as a mechanism for enhancing mechanical properties of engineered articular cartilage. Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society 2013;21:634-41. PDF
Huey DJ, Athanasiou KA. Alteration of the Fibrocartilaginous Nature of Scaffoldless Constructs Formed from Leporine Meniscus Cells and Chondrocytes through Manipulation of Culture and Processing Conditions. Cells, tissues, organs 2013. PDF
Makris EA, Macbarb RF, Responte DJ, Hu JC, Athanasiou KA. A copper sulfate and hydroxylysine treatment regimen for enhancing collagen cross-linking and biomechanical properties in engineered neocartilage. FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2013. PDF
Hadidi P, Athanasiou KA. Enhancing the mechanical properties of engineered tissue through matrix remodeling via the signaling phospholipid lysophosphatidic acid. Biochemical and biophysical research communications 2013;433:133-8. PDF
Wong ML, Wong JL, Athanasiou KA, Griffiths LG. Stepwise solubilization-based antigen removal for xenogeneic scaffold generation in tissue engineering. Acta biomaterialia 2013. PDF
2012
1 In press. Willard, V.P., Kalpakci, K.N., Reimer, A.J., and Athanasiou, K.A. (2012). The regional contribution of glycosaminoglycans to temporomandibular joint disc compressive properties. J Biomech Eng 134, 011011. PDF
2 In press. Arzi, B.; Cissell, D.D.; Verstraete, F.J.M.; Klass, P.H.; DuRaine, G.D.; Athanasiou, K.A. Computed Tomographic Findings in Temporomandibular Joint Disorders in 41 Dogs and 17 Cats: (2006-2011). Journal of the American Veterinary Medical Association. PDF
3 In press. Murphy, M.K.; Huey, D.J.; Reimer, A.J.; Hu, J.; Athanasiou, K.A. Enhancing post-expansion chondrogenic potential of costochondral cells in self-assembled neocartilage. PLoS ONE. PDF
4 In press. DuRaine, G.D.; Athanasiou, K.A. ERK activation is required for hydrostatic pressure induced changes in engineered articular cartilage. Tissue Engineering and Regenerative Medicine. PDF
256. Huey, D.; Hu, J.C.; Athanasiou, K.A. Unlike bone, cartilage regeneration remains elusive. Science, 338(6109). PDF
255. Responte, D.J., Arzi, B., Natoli, R.M., Hu, J.C., and Athanasiou, K.A. (2012). Mechanisms underlying the synergistic enhancement of self-assembled neocartilage treated with chondroitinase-ABC and TGF-beta1. Biomaterials 33, 3187-3194. PDF
254. Sanchez-Adams J, Athanasiou KA. Biomechanics of meniscus cells: regional variation and comparison to articular chondrocytes and ligament cells. Biomech Model Mechanobiol. 2012 Jan 10. [Epub ahead of print] PDF
253. Arzi B, Wisner ER, Huey DJ, Kass PH, Hu J, Athanasiou KA. A proposed model of naturally occurring osteoarthritis in the domestic rabbit. Lab Anim (NY). 2012 41(1):20-5. PDF
252. Sanchez-Adams J, Athanasiou KA. (2012) Dermis isolated adult stem cells for cartilage tissue engineering. Biomaterials. 33(1):109-19. PDF
251. Sanchez-Adams J, Athanasiou KA. Regional Effects of Enzymatic Digestion on Knee Meniscus Cell Yield and Phenotype for Tissue Engineering. Tissue Eng Part C Methods. 2011 Dec 2. PDF
250. Eleswarapu, S.V.; Athanasiou, K.A.: TRPV4 channel activation improves the tensile properties of self-assembled articular cartilage constructs, Acta Biomaterialia, 2012. PDF
249. Responte DJ, Natoli RM, Athanasiou KA. (2012). Identification of potential biophysical and molecular signaling mechanisms underlying hyaluronic acid enhancement of cartilage formation. J R Soc Interface. 9(77):3564-73. PDF
248. Responte, D.J., Lee, J.K., Hu, J.C., and Athanasiou, K.A. (2012). Biomechanics-driven chondrogenesis: from embryo to adult. FASEB J. PDF
247. Dowling EP, Ronan W, Ofek G, Deshpande VS, McMeeking RM, Athanasiou KA, McGarry JP. (2012). The effect and contractility of the actin cytoskeleton on the shear resistance of single cells: a computational and experimental investigation. J R Soc Interface, 9(77):3469-79. PDF
246. Sun, Y., Responte, D., Xie, H., Liu, J., Fatakdawala, H., Hu, J., Athanasiou, K.A., Marcu L. (2012). Nondestructive evaluation of tissue engineered articular cartilage using time-resolved fluorescence spectroscopy and ultrasound backscatter microscopy. Tissue Eng Part C Methods. 2012 Mar;18(3):215-26. PDF
245. MacBarb, R.M.; Makris, E.A.; Hu, J.C.; ATHANASIOU, K.A.: A chondroitinase-ABC and TGF-β1 treatment regimen for enhancing the mechanical properties of tissue engineered fibrocartilage, Acta Biomaterialia, S1742-7061(12): 00523-5, 2012. PDF
244. Huey, D.J., Sanchez-Adams, J., Willard, V.P., Athanasiou, K.A. (2012) Immunogenicity of Bovine and Leporine Articular Chondrocytes and Meniscus Cells. Tissue Eng Part A. Mar;18(5-6):568-75. PDF
243. Willard VP, Arzi B, Athanasiou KA. The attachments of the temporomandibular joint disc: A biochemical and histological investigation. Arch Oral Biol. 57(6):599-606, 2012 PDF
242. Arzi, B.; Willard, P.V.; Huey, D.J.; Verstraete, F.J.M.; Vapniarsky-Arzi, N.; Athanasiou , K.A. The Temporomandibular Joint Disc of Asian Elephant (Elephas Maximus) and African Elephant (Loxodonta Africana). European Journal of Wildlife Research, 58(2): 451-459, 2012 PDF
241. Huey, D.; Hu, J.C.; Athanasiou , K.A. Chondrogenically-Tuned Expansion Enhances the Cartilaginous Matrix forming Capabilities of Primary, Adult, Leporine Chondroytes in the Self-Assembly Modality. Cell Transplantation, CT-0545: DOI:10.3727/0963689. PDF
240. McNary, S., Athanasiou, K.A., Reddi, A.H. Engineering Lubrication in Articular Cartilage. Tissue Engineering: Part B Volume 18, Number 2, 2012 PDF
Editorial. Athanasiou, K.A. (2012). A new form of specialization. Ann Biomed Eng 40, 1627. PDF
2011
239. Murphy, M.; MacBarb, R.F.; ATHANASIOU, K.A. Temporomandibular Joint Disorders: A Review of Etiology, Clinical Management, and Tissue Engineering Strategies. Oral & Craniofacial Tissue Engineering, 1(3): 205-226. text
238. Eleswarapu SV, Responte DJ, Athanasiou KA. Tensile properties, collagen content, and crosslinks in connective tissues of the immature knee joint. PLoS One. 2011;6(10):e26178. Epub 2011 Oct 13. PDF
237. Sanchez-Adams J, Willard VP, Athanasiou KA. Regional variation in the mechanical role of knee meniscus glycosaminoglycans. J Appl Physiol. 2011 Sep 8. PDF
236. Huey DJ, Athanasiou KA. Tension-compression loading with chemical stimulation results in additive increases to functional properties of anatomic meniscal constructs. PLoS One. 2011;6(11):e27857. Epub 2011 Nov 16. PDF
235. Wong, M.L., Leach, J.K., Athanasiou, K.A., Griffiths, L.G. (2011) The role of protein solubilization in antigen removal from xenogeneic tissue for heart valve tissue engineering. Biomaterials. Nov;32(32):8129-38. PDF
234. Eleswarapu SV, Chen JA, Athanasiou KA. Temporal assessment of ribose treatment on self-assembled articular cartilage constructs. Biochem Biophys Res Commun. 2011 Oct 22;414(2):431-6. Epub 2011 Sep 28. PDF
233. Makris EA, Hadidi P, Athanasiou KA. The knee meniscus: Structure-function, pathophysiology, current repair techniques, and prospects for regeneration. Biomaterials. 2011. PDF
232. Bhatavadekar NB, Hu J, Keys K, Ofek G, Athanasiou KA. Novel application of cytodetachment technology to the analysis of dental implant surfaces. Int J Oral Maxillofac Implants. 2011 Sep-Oct;26(5):985-90. PDF
231. Kalpakci KN, Kim EJ, Athanasiou KA. Assessment of growth factor treatment on fibrochondrocyte and chondrocyte co-cultures for TMJ fibrocartilage engineering. Acta Biomater. Acta Biomater. 7(4):1710-8, 2011. PDF
230. Huey DJ, Athanasiou KA. Biomaterials. Maturational growth of self-assembled, functional menisci as a result of TGF-β1 and enzymatic chondroitinase-ABC stimulation. Biomaterials. 32(8):2052-8, 2011. PDF
229. Kalpakci KN, Willard VP, Wong ME, Athanasiou KA. An Interspecies Comparison of the Temporomandibular Joint Disc. J Dent Res. J Dent Res. 90(2):193-8, 2010. PDF
228. Elder, B.D.; Mohan A.; ATHANASIOU, K.A.: Beneficial effects of exogenous crosslinking agents on self-assembled tissue engineered cartilage construct biomechanical properties. Journal of Mechanics in Medicine and Biology, DOI 10.1142/S0219519410003769, 11(2):433-443, 2011 PDF
227. Natoli RM, Skaalure S, Bijlani S, Chen KX, Hu J, Athanasiou KA. Intracellular Na(+) and Ca(2+) modulation increases the tensile properties of developing engineered articular cartilage. Arthritis Rheum. 62(4):1097-107, 2010. PDF
226. Feng Y, Ofek G, Choi DS, Wen J, Hu J, Zhao H, Zu Y, Athanasiou KA, Chang CC. Unique biomechanical interactions between myeloma. Prog Biophys Mol Biol. 103(1):148-56, 2010. PDF
225. Elder BD, Kim DH, Athanasiou KA. Developing an articular cartilage decellularization process toward facet joint cartilage replacement. Neurosurgery. 66(4):722-7, 2010. PDF
224. Gunja NJ, Athanasiou KA. Additive and synergistic effects of bFGF and hypoxia on leporine meniscus cell-seeded PLLA scaffolds. J Tissue Eng Regen Med. 4(2):115-22, 2010. PDF
223. Gunja, N.J.; ATHANASIOU, K.A.: Effects of hydrostatic pressure on leporine meniscus cell-seeded PLLA scaffolds. Journal of Biomedical Materials Research, Part A, 92(3): 896-905, 2010. PDF
Editorial. Athanasiou KA. Passing the baton to the Davis Editorial Office–January 2010. Ann Biomed Eng. 38(1):1, 2010. PDF
Editorial. Athanasiou KA. Special issues. Ann Biomed Eng. Ann Biomed Eng. 39(6):1607, 2011. PDF
Chapter 5. MacBarb, R.F.; Murphy, M.K.; Athanasiou, K.A.: Temporomandibular Joint: Structure, Function, and Current Perspectives, Beth Winkelstein, (ed), Orthopaedic Biomechanics. Text
Chapter 4. DuRaine, G.; Hu, J.C.; Athanasiou, K.A.: Bioengineering the Oral Cavity: Insights from Articular Cartilage Tissue Engineering, International Journal of Oral & Maxillofacial Implants, Vol. 26, pp. 11-19. PDF
Chapter 3. Olson SA, Brown TD, Athanasiou, KA, Natoli RM, Dirschl DR. Applied biomechanics in articular injuries: perspectives in the basic investigation of articular injuries and clinical application. Instr Course Lect. 60:583-94, 2011. Text
Chapter 2. Sanchez-Adams, J.; Athanasiou, K.A.: Biomechanical characterization of single chondrocytes. In book Cellular and Biomolecular Mechanics and Mechanobiology, Amit Gefen, (ed), Studies in Mechanobiology, Tissue Engineering and Biomaterials, Vol. Chapt. 20, Springer, pp. 248-266. PDF
Chapter 1. Willard, V.P.; Zhang, L.; Athanasiou, K.A.: Tissue Engineering of the Temporomandibular Joint, D. Ducheyne, K. Healy, D. Hutmacher, and J. Kirkpatrick, (ed), Comprehensive Biomaterials, Elsevier. PDF
2009
Ofek G.; Wiltz, D.C.; Athanasiou, K.A.: Contribution of the cytoskeleton to the compressive properties and recovery behavior of single cells, Biophysical Journal, In Press, 97(7): , 2009. PDF
Natoli RM, Athanasiou KA. Traumatic loading of articular cartilage: Mechanical and biological responses and post-injury treatment. Biorheology. 46(6):451-85, 2009.
Ofek, G.; Dowling, E.P.; Raphael, R.M.; McGarry, J.P.; ATHANASIOU, K.A.: Biomechanics of single chondrocytes under direct shear, Biomechanics and Modeling in Mechanobiology, DOI 10.1007/s10237-009-0166-1, 2009. PDF
Sanchez-Adams, J.; ATHANASIOU, K.A.: The knee meniscus: A complex tissue of diverse cells, Cellular and Molecular Bioengineering, DOI 10.1007/s12195-009-0066-6, 2009.
Gunja, N.J.; Huey, D.; James, R.; ATHANASIOU, K.A.: Effects of agarose mold compliance and surface roughness on self-assembled meniscus-shaped constructs, Journal of Tissue Engineering and Regenerative Medicine, Accepted, 2009. PDF
Natoli, R.M.; Revell, C.R.; ATHANASIOU, K.A.: Chondroitinase-ABC treatment results in increased tensile properties of self-assembled tissue engineered articular cartilage. Tissue Engineering, In Press, 2009. PDF
Elder, B.D.; Vigneswaran, K.; ATHANASIOU, K.A.; Kim, DH: Biomechanical, biochemical, and histological characterization of canine lumbar facet joint cartilage. Journal of Neurosurgery Spine. 10:623-628, 2009. PDF
Koay, E.J.; ATHANASIOU, K.A.: Articular cartilage biomechanics, mechanobiology, and tissue engineering. Biomechanical Systems Technology: Muscular Skeletal Systems (World Scientific), pp. 1-37, 2009.
Elder, B.D.; ATHANASIOU, K.A.: Effects of temporal hydrostatic pressure on tissue engineered bovine articular cartilage constructs. Tissue Engineering Part A, 15(5):1151-1158, doi:10.1089/ten.tea.2008.0200, 2009. PDF
Ofek, G.; Natoli, R.M.; ATHANASIOU, K.A.: In situ mechanical properties of the chondrocyte cytoplasm and nucleus. Journal of Biomechanics, 42:873-877, 2009. PDF
Elder, B.D.; Eleswarapu, S.V.; ATHANASIOU, K.A.: Evaluating extraction techniques for the decellularization of tissue engineered articular cartilage constructs. Biomaterials, 30:3749-3756, doi:10.1016/j.biomaterials.2009.03.050, 2009. PDF
Responte, D.; Natoli, R.M.; ATHANASIOU, K.A.: Collagens of articular cartilage: structure, function, and importance in tissue engineering, Critical Reviews in Biomedical Engineering, 35(5):363-411, 2009.
Gunja, N.J.; ATHANASIOU, K.A.: Effects of co-cultures of meniscus cells and articular chondrocytes on PLLA scaffolds. Biotechnology and Bioengineering, 103(4):808-816, DOI 10.1002/bit.22301, 2009. PDF
Ofek, G.; Willard, V.P.; Koay, E.J.; Hu, J.C.; Lin, P.; ATHANASIOU, K.A.: Mechanical characterization of differentiated human embryonic stem cells. Journal of Biomechanical Engineering, 131(6), 061011 DOI:10.1115/1.3127262, 2009. PDF
Koay, E.J.; ATHANASIOU, K.A.: Development of serum-free, chemically defined conditions for human embryonic stem cell-derived fibrochondrogenesis. Tissue Engineering Part A, 15(8):2249-2257, doi:10.1089/ten.tea.2008.0320, 2009. PDF
DiCarlo, B.B.; Hu, J.C.; Gross, T.; Vago, R.; ATHANASIOU, K.A.: Biomaterial effects in articular cartilage tissue engineering using polyglycolic acid, a novel marine origin biomaterial, IGF-I, and TGF-β1: Proc. IMechE, Part H: J. Engineering in Medicine, 223(H1):63-73. DOI: 10.1243/09544119JEIM424, 2009.
Anderson (Johns), D.E. and ATHANASIOU, K.A.: A comparison of primary and passaged chondrocytes for use in engineering the temporomandibular joint. Archives of Oral Biology, 54:138–145, 2009. PDF
Elder, B.D.; ATHANASIOU, K.A.: Hydrostatic pressure in articular cartilage tissue engineering: From chondrocytes to tissue regeneration, Tissue Engineering, Part B: Reviews, 15(1):43-53. doi:10.1089/ten.teb.2008.0435, 2009. PDF
Gunja, N.J.; Uthamanthil, R.K.; ATHANASIOU, K.A.: Effects of TGF-beta 1 and hydrostatic pressure application on meniscus cell-seeded scaffolds, Biomaterials, 30:565-573, 2009. PDF
Elder, B.D.; ATHANASIOU, K.A.: Systematic assessment of growth factor treatment on biochemical and biomechanical properties of engineered articular cartilage constructs. Osteoarthritis and Cartilage, 17:114-123, 2009. PDF
Deng, Y., Gunja, N.J., ATHANASIOU, K.A.: “Perspectives and possibilities for degradable polymers for skeletal implants” In Degradable polymers for skeletal implants. Nova Science Publishers Inc. Hauppage, NY Editors: Wuisman, P and Smit, T.
Natoli, R.M.; Responte, D.; ATHANASIOU, K.A.: Effects of multiple chondroitinase ABC applications on tissue engineered articular cartilage. Journal of Orthopedic Research, 27(7):949-956, http://www3.interscience.wiley.com/cgi-bin/fulltext/121606154/PDFSTART, 2009.
Zhang, L., Hu, J., Athanasiou, K.A. The Role of Tissue Engineering in Articular Cartilage Repair and Regeneration. Crit Rev Biomed Eng. 2009;37(1-2):1-57. PDF
Revell, C.M., ATHANASIOU, K.A.: Success rates and immunologic responses of autogenic, allogenic, and xenogenic treatments to repair articular cartilage defects. Tissue Engineering Part B: Reviews, 15(1):1-15, doi:10.1089/ten.teb.2008.0189, 2009.
2008
Anderson (Johns), D.E. and ATHANASIOU, K.A.: Passaged goat costal chondrocytes provide a feasible cell source for temporomandibular joint tissue engineering. Annals of Biomedical Engineering, 36(12):1992-2001, 2008.
Hoben, G.M.; ATHANASIOU, K.A.: Use of staurosporine, an actin modifying agent, to enhance fibrochondrocyte matrix gene expression and synthesis. Cell and Tissue Research, 334(3):469-476, 2008.
Ofek, G.; Revell, C.M.; Hu, J.C.; Allison, D.D.; Grande-Allen, K.J.; ATHANASIOU, K.A.: Matrix development in self-assembly of articular cartilage. PLoS ONE, 3(7): e2795. doi:10.1371/journal.pone.0002795, 2008.
Gunja, N.J.; ATHANASIOU, K.A.: A survey of salient biodegradable ACL interference screws. In The Anterior Cruciate Ligament: Reconstruction and Basic Science, C. Prodromos, Editor. 2008.
Revell, C.M.; Reynolds, C.E.; ATHANASIOU, K.A.: Effects of initial cell seeding in self assembly of articular cartilage. Annals of Biomedical Engineering, 36(9):1441-1448, 2008.
Elder, B.D.; ATHANASIOU, K.A.: Synergistic and additive effects of hydrostatic pressure and growth factors on tissue formation. PLoS ONE, 3(6): e2341. doi:10.1371/journal.pone.0002341, 2008.
Johns, D.E. and Athanasiou, K.A.: Growth factor effects on costal chondrocytes for tissue engineering fibrocartilage. Cell and Tissue Research, 333:439–447, 2008.
Gross-Aviv, T; DiCarlo, B.; French, M.; ATHANASIOU K.A.; and Vago R.: Crystalline biomaterials for articular cartilage bioengineering. Materials Science and Engineering C, 28:1388–1400, 2008.
Hoben, G.M.; Willard, V.; ATHANASIOU, K.A.: Fibrochondrogenesis of hESCs: Growth factor combinations and co-cultures. Stem Cells and Development, 18(2):283-292, 2009. PDF
Koay, E.J.; ATHANASIOU, K.A.: Hypoxic chondrogenic differentiation of human embryonic stem cells enhances cartilage protein synthesis and biomechanical functionality. Osteoarthritis and Cartilage, (http://dx.doi.org/10.1016/j.joca.2008.04.007), 16:1450-1456, 2008.
Natoli, R.; ATHANASIOU, K.A.: P188 reduces cell death and IGF-I reduces GAG release following single-impact loading of articular cartilage. Journal of Biomechanics, 130:041012-1 to041012-9, 2008.
Blumberg T.J.; Natoli R.; ATHANASIOU, K.A.: Effects of doxycycline on articular cartilage GAG release and mechanical properties following impact. Biotechnology and Bioengineering, 100(3):506-515, 2008.
Hoben, G.M.; ATHANASIOU, K.A.: Creating a spectrum of fibrocartilages through different cell sources and biochemical stimuli. Biotechnology and Bioengineering, 100(3):587-598, 2008.
Johns, D.E. and ATHANASIOU, K.A.: Clinically-relevant cell sources for TMJ disc engineering. Journal of Dental Research, Res 87(6):548-552, 2008.
Natoli, R.; Scott, C.C.; ATHANASIOU, K.A.: Temporal effects of impact on articular cartilage cell death, gene expression, matrix biochemistry, and biomechanics. Annals of Biomedical Engineering, 36(5):780-792, 2008.
Hoben, G.M.; Koay, E.J.; ATHANASIOU, K.A.: Fibrochondrogenesis in two embryonic stem cell lines: Effects of differentiation timelines. Stem Cells, 26(2):422-430, 2008.
Allen, K.D.; ATHANASIOU, K.A.: Scaffold and growth factor selection in temporomandibular joint disc engineering, Journal of Dental Research, 87(2):180-185, 2008.
Allen, K.D.; Erickson, K.; ATHANASIOU, K.A.: The effects of protein coated surfaces on passaged porcine TMJ disc cells, Archives of Oral Biology, 53:53-59, 2008.
Koay, E.J.; Ofek, G.; ATHANASIOU, K.A.: Effects of TGF-β1 and IGF-I on the compressibility, biomechanics, and strain-dependent behavior of single chondrocytes. Journal of Biomechanics, 41:1044-1052, 2008.
Leipzig, N.; ATHANASIOU, K.A.: Static compression of single chondrocytes catabolically modifies single cell gene expression. Biophysical Journal, 94(6):2412-2422, 2008.
Elder, B.D.; ATHANASIOU, K.A.: Paradigms of tissue engineering with applications to cartilage regeneration, In W. Pietrzak, Ed., Musculoskeletal Tissue Regeneration: Biological Materials and Methods, Chapter 28, pp:593-615, 2008.
Gunja, N.; ATHANASIOU, K.A.: Passage and recovery effects on gene expression of meniscal fibrochondrocytes. Arthritis Research & Therapy, 9:R93, 2007.
Aufderheide, A.; ATHANASIOU, K.A.: Assessment of a bovine co-culture, scaffold-free method for growing meniscus-shaped constructs. Tissue Engineering, 13(9):2195-2205, 2007.
Elder, B.D.; ATHANASIOU, K.A.: Effects of confinement on the mechanical properties of self-assembled articular cartilage constructs in the direction orthogonal to the confinement surface, Journal of Orthopaedic Research, Published Online: 29 Aug 2007 DOI: 10.1002/jor.20480, 26(2): 238-246, 2007.
Koay, E.J.; Hoben, G.M.; ATHANASIOU, K.A.: Tissue engineering with chondrogenically-differentiated human embryonic stem cells. Stem Cells, 25:2183–2190, 2007.
Koay, E.J.; ATHANASIOU, K.A.: Effects of TGF-β1 and IGF-I on the compressibility, biomechanics, and strain-dependent behavior of single chondrocytes. Journal of Biomechanics, 41:1044-1052, 2008.
2007
Hoben, G.M.; Hu, J.; James, R.; ATHANASIOU, K.A.: Self-assembly of fibrochondrocytes and chondrocytes for tissue engineering of the knee meniscus. Tissue Engineering, 13(5):939-946, 2007.
Detamore, M.S.; ATHANASIOU, K.A.; Mao, J.J.: A call to action for bioengineers and dental professionals: directives for the future of TMJ bioengineering. Annals of Biomedical Engineering, 35(8): 1301-1311, 2007.
Young, S.; ATHANASIOU, K.A.; Mikos, A.; Wong, M.E.: Tissue engineering in oral and maxillofacial surgery, In ‘Principles of Tissue Engineering’, 3rd Edition, Editors: Robert Lanza, Robert Langer, and Joseph P. Vacanti, 2007.
Ofek, G.; ATHANASIOU, K.A.: Micromechanical properties of chondrocytes and chondrons: relevance to articular cartilage tissue engineering, Journal of Mechanics of Materials and Structures (special issue of Mechanics of Biomaterials in Small Length-Scale), 2(6):1059-1086, 2007.
Eleswarapu, S.V.; Leipzig, N.; ATHANASIOU, K.A.: Gene expression of single articular chondrocytes. Cell and Tissue Research, 327(1):43-54, 2007.
Lavery, L.; Higgins, K.R.; Lanctot, D.R.; Constantinides, G.P.; Zamorano, R.G.; ATHANASIOU, K.A.; Armstrong, D.G.; Agrawal, C.M: Preventing diabetic foot ulcer recurrence in high risk diabetic patients: use of temperature monitoring as a self-assessment tool. Diabetes Care, 30(1): 14-20, 2007.
Johns, D.; ATHANASIOU, K.A.: Improving culture conditions for TMJ disc tissue engineering. Cells, Tissues, Organs, 185(4):246-257, 2007.
Deng, Y.; Hu, J.C.; ATHANASIOU, K.A.: Isolation and chondroinduction of a dermis-isolated, aggrecan sensitive subpopulation with high chondrogenic potential, Arthritis & Rheumatism, 56(1):168-176, 2007
Edwards, R.B.; Lu, Y.; Uthamanthil, R.K.; Bogdanske, J.J.; Muir, P.; ATHANASIOU, K.A.; Markel, M.D.: Comparison of mechanical debridement and radiofrequency energy for chondroplasty in an in vivo equine model of partial thickness cartilage injury. Osteoarthritis and Cartilage. 15(2):169-178, 2007.
Shieh, A.; ATHANASIOU, K.A.: Dynamic compression of single cells. Osteoarthritis and Cartilage, 15: 328-334, 2007.
Allen, K.D.; ATHANASIOU, K.A.: Effect of passage and topography on gene expression of TMJ disc cells. Tissue Engineering, 13(1):101-110, 2007.
2006
Leipzig, N.; Eleswarapu, S.V.; ATHANASIOU, K.A.: The effects of TGF-β1 and IGF-I on the biomechanics and cytoskeleton of single chondrocytes. Osteoarthritis and Cartilage, 14:1227-1236, 2006.
Scott, C.C.; ATHANASIOU, K.A.: Mechanical impact and articular cartilage. Critical Reviews in Biomedical Engineering, 34(5):347-78, 2006.
Revell, C.M.; Dietrich, J.; Scott, C.C.; Luttge, A.; ATHANASIOU, K.A.: Characterization of fibroblast morphology on bioactive surfaces using vertical scanning interferometry. Matrix Biology, 25(8): 523-533 2006.
Allen, K.D.; ATHANASIOU, K.A.: Growth factor effects on passaged TMJ disc cells in monolayer and pellet cultures. Orthodontics and Craniofacial Research, 9(3):143-52, 2006.
Aufderheide, A.; ATHANASIOU, K.A.: A direct compression stimulator for articular cartilage and meniscal explants. Annals of Biomedical Engineering, 34(9):1463-1474, 2006.
Scott, C.C.; ATHANASIOU, K.A.: Design, validation, and utilization of an articular cartilage impact instrument. Journal of Engineering in Medicine, 220(8):845-855, 2006.
Hu, J.C.; ATHANASIOU, K.A.: Chondrocytes from different zones exhibit characteristic differences in high density culture. Connective Tissue Research, 47(3):133-140, 2006.
Gunja, N.; ATHANASIOU, K.A.: Biodegradable materials in arthroscopy. Sports Medicine & Arthroscopy Review. 14(3):112-119, 2006.
Scott, C.C.; Volz, T.; ATHANASIOU, K.A.: Learning how to teach continuum biomechanics: See one, do one, teach one. Journal of Engineering Education, 22(1):183-187, 2006.
Hoben, G.M.; ATHANASIOU, K.A.: Meniscal repair with fibrocartilage engineering. Sports Medicine & Arthroscopy Review, 14(3):129-137, 2006.
Hayman, D.M.; Blumberg, T.J.; Scott, C.C.; ATHANASIOU, K.A.: The effects of isolation on chondrocyte gene expression, Tissue Engineering, 12(9):2573-2581, 2006.
Detamore, M.S.; Hegde, J.N.; Wagle, R.R.; Almarza, A.J.; Montufar-Solis, D.; Duke, P.J.; ATHANASIOU, K.A.: Cell type and distribution in the porcine temporomandibular joint disc. Journal of Oral and Maxillofacial Surgery, 64:243-248, 2006
Fleischli, J.G.; Laughlin, T.J.; ATHANASIOU, K.A.; Lanctot, D.R.; Lavery, L.; Wang, X.; Agrawal, C.M: The effect of diabetes mellitus on the material properties of the distal tibia, Journal of American Podiatric Medical Association, 96(2):91-95, 2006.
Allen, K.D.; ATHANASIOU, K.A.: Tissue engineering the TMJ disc: A review, Tissue Engineering, 12(5):1183 -1196, 2006.
Johns, D.E., Willard, V.P., Allen, K.D., and ATHANASIOU, K. A.: Is tissue engineering of the TMJ disc a feasible process? Chapter in book ‘International Conference on TMJ Replacement and Tissue Engineering in Hiroshima’, p 37-47, 2006.
Allen, K.D.; ATHANASIOU, K.A.: Viscoelastic characterization of the porcine temporomandibular joint disc under unconfined compression. Journal of Biomechanics, 39:312-322, 2006.
Hu, J.C.; ATHANASIOU, K.A.: The effects of intermittent hydrostatic pressure on self-assembled articular cartilage constructs. Tissue Engineering, 12(5): 1337 -1344, 2006.
Hu, J.C.; ATHANASIOU, K.A.: A self-assembling process in articular cartilage tissue engineering. Tissue Engineering, 12(4):969-979, 2006.
Bean, A.C.; Almarza, A.J.; ATHANASIOU, K.A.: Effects of ascorbic acid concentration for the tissue engineering of the temporomandibular joint disc. Journal of Engineering in Medicine, 220:439-447, 2006.
Uthamanthil, R.K.; Edwards, R.B.; Lu, Y.; Manley, P.A.; ATHANASIOU, K.A.; Markel, M.D.: In vivo study on the short-term effect of radiofrequency energy on chondromalacic patellar cartilage and its correlation with calcified cartilage pathology in an equine model. Journal of Orthopaedic Research, 24:716-724, 2006.
Almarza, A.J.; ATHANASIOU, K.A.: Evaluation of three growth factors in combinations of two for TMJ disc tissue engineering. Archives of Oral Biology, 51(3):215-221, 2006.
Almarza, A.J.; ATHANASIOU, K.A.: Effects of hydrostatic pressure on TMJ disc cells. Tissue Engineering, 12(5):1285-1294, 2006.
Shieh, A.C.; Koay, E.J.; ATHANASIOU, K.A.: Strain-dependent recovery behavior of single chondrocytes, Biomechanics and Modeling in Mechanobiology, 5(2-3):172-179, 2006.
Shieh, A.C.; ATHANASIOU, K.A.: Biomechanics of single zonal chondrocytes. Journal of Biomechanics, 39(9):1595-1602, 2006.
2005
Darling, E.M.; ATHANASIOU, K.A.: Growth factor impact on articular cartilage subpopulations. Cell and Tissue Research, 322:463-473, 2005.
Sweigart, M.A.; ATHANASIOU, K.A.: Tensile and compressive properties of the medial rabbit meniscus. Journal of Engineering in Medicine, 219(5):337-348, 2005.
Allen, K.D.; ATHANASIOU, K.A.: A surface-regional and freeze-thaw characterization of the porcine temporomandibular joint disc. Annals of Biomedical Engineering, 33(7):951-962, 2005.
Lavery, L.A.; Lanctot, D.R.; Constantinides, G.P.; Zamorano, R.G.; ATHANASIOU, K.A.; Agrawal, C.M.: Wear and biomechanical characteristics of a novel shear-reducing insole with implications for high-risk persons with diabetes. Diabetes Technology & Therapeutics, 7(4):638-646, 2005.
Wang, L.; Kalu, D.N.; Banu, J.; Thomas, J.B.; Gabriel, N.; ATHANASIOU, K.A.: Effects of aging on the biomechanical properties of rat articular cartilage. Journal of Engineering in Medicine, 220:573-578, 2006.
Pangborn, A.C.; ATHANASIOU, K.A.: Growth factors and fibrochondrocytes in scaffolds. Journal of Orthopaedic Research, 23(5):1184-1190, 2005.
Almarza, A.J.; ATHANASIOU, K.A.: Effects of initial seeding density for the tissue engineering of the temporomandibular joint disc. Annals of Biomedical Engineering, 33(7):943-950, 2005.
Hu, J.C.Y.; ATHANASIOU, K.A.: Effect of scaffold microenvironment on low-density chondrocyte bioreactor culture. Biomaterials, 26(14):2001-2012, 2005.
Shieh, A.; ATHANASIOU, K.A.: Musculoskeletal cell mechanics. The Wiley Encyclopedia of Biomedical Engineering, Metin Akay (ed.), John Wiley & Sons, 2006.
Wong, M; Allen, K.; ATHANASIOU, K.A.: Tissue engineering of the temporomandibular joint. In: The Biomedical Engineering Handbook – Tissue Engineering and Artificial Organs (Third Edition), Joseph D. Bronzino (ed.), CRC Press, Boca Raton, FL, pgs 52-1 through 52-22, 2006.
Detamore, M.S.; ATHANASIOU, K.A.: Use of a rotating bioreactor toward tissue engineering of the temporomandibular joint disc. Tissue Engineering, 11(7-8):1188-1197, 2005.
Almarza, A.J.; Bean, A.; Baggett, S.; ATHANASIOU, K.A.: Biochemical characteristics of the porcine temporomandibular joint disc. British Journal of Oral and Maxillofacial Surgery, 44(2):124-128, 2006. PDF
AufderHeide, A.; ATHANASIOU, K.A.: A comparison of scaffolds and culture conditions for tissue engineering of the knee meniscus. Tissue Engineering, 11(7-8):1095-1104, 2005.
Leipzig, N.D.; ATHANASIOU, K.A.: Unconfined creep compression of chondrocytes. Journal of Biomechanics, 38(1):77-85, 2005. PDF
Detamore, M.S.; Orfanos, J.G.; Almarza, A.J.; French, M.M.; Wong, M.E.; ATHANASIOU, K.A.: Quantitative analysis and comparative regional investigation of the extracellular matrix of the porcine temporomandibular joint disc. Matrix Biology, 24:45-57, 2005.
Allen, K.; Detamore, M.; Almarza, A.; Wong, M; ATHANASIOU, K.A.: The temporomandibular joint disc. The Wiley Encyclopedia of Biomedical Engineering, Metin Akay (ed.), John Wiley & Sons, 2006.
Pangborn, C.; ATHANASIOU, K.A.: The knee meniscus. Wiley Encyclopedia of Biomedical Engineering, Metin Akay (ed.), Wiley-Interscience; 1 edition (April 28, 2006).
Pangborn, A.C.; ATHANASIOU, K.A.: Effects of growth factors on meniscal fibrochondrocytes in monolayer cultures. Tissue Engineering, 11(7-8):1141-1148, 2005.
Darling, E.; ATHANASIOU, K.A.: Retaining zonal chondrocyte phenotype using novel growth environments. Tissue Engineering, 11(3-4):395-403, 2005.
Detamore, M.S.; ATHANASIOU, K.A.: Evaluation of three growth factors for TMJ disc tissue engineering. Annals of Biomedical Engineering, 33(3):383-390, 2005.
Scott, C.C.; Luttge, A.; ATHANASIOU, K.A: Development and validation of vertical scanning interferometry as a novel method for acquiring chondrocyte geometry. Journal of Biomedical Materials Research: Part A, 72A(1):83-90, 2005.
Darling, E.; ATHANASIOU, K.A.: Rapid phenotypic changes in passaged articular chondrocyte subpopulations. Journal of Orthopaedic Research, 23(2):425-432, 2005. PDF
Sweigart, M.A.; ATHANASIOU, K.A.: Biomechanical characteristics of the normal medial and lateral porcine knee menisci. Journal of Engineering in Medicine, 219:53-62, 2005.
2004
Lo, K.Y.; Burkhart, S.S.; ATHANASIOU, K.A.: Abrasion resistance of two types of non-absorbable braided sutures, Arthroscopy: The Journal of Arthroscopic and Related Surgery, 20(4):407-413, 2004.
Lavery, L.A.; Lanctot, D.R.; Constantinides, G.P.; Zamorano, R.G.; ATHANASIOU, K.A.; Agrawal, C.M.: Home monitoring of foot skin temperatures to prevent recurrent ulceration, Diabetes Care, 27:2642-2647, 2004.
Sweigart, M.A.; Zhu, C.F.; Burt, D.M.; deHoll, P.D.; Agrawal, C.M.; Clanton, T.C.; ATHANASIOU, K.A.: Interspecies comparison of the creep indentation biomechanics of the medial meniscus. Annals of Biomedical Engineering, 32(11): 1569-1579, 2004.
Hu, J.C.Y.; ATHANASIOU, K.A.: Functional assessment of articular cartilage. In Tissue Engineering in Musculoskeletal Clinical Practice. Ed by LJ Sandell and AJ Grodzinsky, Chapter 23 (pp. 227-233), Published by the American Academy of Orthopaedic Surgeons, 2004.
Leipzig, N.; ATHANASIOU, K.A.: Cartilage regeneration, The Encyclopedia of Biomaterials and Biomedical Engineering, Marcel Dekker, Inc. pp:283-291, 2004.
Lo, K.Y.; Burkhart, S.S.; Chan, K.C.; ATHANASIOU, K.A.: Arthroscopic knots: Determining the optimal balance of loop security and knot security. Arthroscopy: The Journal of Arthroscopic and Related Surgery, 20(5):489-502, 2004.
Almarza, A.J.; ATHANASIOU, K.A.: Seeding techniques and scaffolding choice for the tissue engineering of the temporomandibular joint disc. Tissue Engineering, 10(11-12): 1787-1795, 2004.
AufderHeide, A.; ATHANASIOU, K.A.: Mechanical stimulation toward tissue engineering of the knee meniscus. Annals of Biomedical Engineering, 32 (8): 1163-1176, 2004.
Almarza, A.J.; Detamore, M.S.; Allen, K.D.; ATHANASIOU, K.A.: Tissue engineering concerns and efforts with the TMJ disc. TMJ Science. 2004 (http://www.tmj.org/TMJdisc_tissue_eng.rtf)
Darling, E.; Hu, J.C.Y.; ATHANASIOU, K.A.: Zonal and topographical differences in articular cartilage gene expression. Journal of Orthopaedic Research, 22(6):1182-1187, 2004.
Niederauer, G.G.; Niederauer, G.M.; Cullen, L.C.; ATHANASIOU, K.A.; Thomas, J.B.; Niederauer, M.Q.: Correlation of cartilage stiffness to thickness and level of degeneration using a hand-held indentation probe. Annals of Biomedical Engineering, 32(3):352-359, 2004.
Detamore, M.S.; ATHANASIOU, K.A.: Effects of growth factors on temporomandibular joint disc cells. Archives of Oral Biology, 459:577-583, 2004.
French, M.M.; Rose, S.; Canseco, J; ATHANASIOU, K.A.: Chondrogenic differentiation of adult dermal fibroblasts. Annals of Biomedical Engineering, 32(1):50-56, 2004.
Almarza, A.; ATHANASIOU, K.A.: Design characteristics for the tissue engineering of cartilaginous tissues. Annals of Biomedical Engineering, 32(1):2-17, 2004.
2003
Darling, E.M.; ATHANASIOU, K.A.: Biomechanical strategies for articular cartilage regeneration, Annals of Biomedical Engineering, 31:1114-1124, 2003.
Detamore, M.S.; ATHANASIOU, K.A.: Tensile properties of the porcine temporomandibular joint disc. Journal of Biomechanical Engineering, 125(4):558-565, 2003.
Kim, K.; Wong, M.E.; Helfrick, J.F.; ATHANASIOU, K.A.: Biomechanical tissue characterization of the superior joint space of the porcine temporomandibular joint. Annals of Biomedical Engineering, 31:924-930, 2003.
Darling, E.M.; ATHANASIOU, K.A.: Bioactive scaffold design for cartilage engineering. In Biomedical Technology and Devices Handbook. Ed by Moore J, Zouridakis G. Chapter 21. Boca Raton, FL: CRC Press. 2003.
Koay, E.J; Shieh, A.; ATHANASIOU, K.A.: Creep indentation of single cells, Journal of Biomechanical Engineering, 125:334-341, 2003.
Detamore, M.S.; ATHANASIOU, K.A.: Motivation, characterization and strategy for tissue engineering the temporomandibular joint disc, Tissue Engineering, 9(6):1065-1087, 2003.
Scott, C.C; ATHANASIOU, K.A.: Shear stress and chondrocytes. In Biomedical Technology and Devices Handbook. Ed by Moore J, Zouridakis G. Chapter 20. Boca Raton, FL: CRC Press. 2003.
Huang, W.; Anvari, B.; Torres, J.H.; LeBaron, R.G.; ATHANASIOU, K.A.: Temporal effects of cell adhesion on mechanical characteristics of the single chondrocyte. Journal of Orthopaedic Research, 21(1):88-95, 2003.
Shieh, A.; ATHANASIOU, K.A.: Principles of cell mechanics for cartilage tissue engineering. Annals of Biomedical Engineering, 31(1):1-11, 2003.
Buckwalter, J.A.; Martin, J.A.; Olmstead, M.; ATHANASIOU, K.A.; Mow, V.C.: Osteochondral repair of primate knee femoral and patellar articular cartilage: Implications for preventing post-traumatic osteoarthritis. The Iowa Orthopaedic Journal, 23:66-74, 2003.
Darling, E.M.; ATHANASIOU, K.A.: Articular cartilage bioreactors and bioprocesses, Tissue Engineering, 9(1):9-26, 2003.
Detamore, M.S.; ATHANASIOU, K.A.: Structure and function of the temporomandibular joint disc: Implications for tissue engineering, Journal of Oral and Maxillofacial Surgery, 61:494-506, 2003.
Sweigart, M.A.; AufderHeide, A.; ATHANASIOU, K.A.: Fibrochondrocytes and their use in tissue engineering of the meniscus, Topics in Tissue Engineering, e-book, http://www.oulu.fi/spareparts/ebook_topics_in_t_e/abstracts/sweigart_1.pdf, Eds. N. Ashammakhi and P. Ferretti, 2003.
French, M.M.; ATHANASIOU, K.A.: Differentiation factors and articular cartilage regeneration, Topics in Tissue Engineering, e-book, http://www.oulu.fi/spareparts/ebook_topics_in_t_e/abstracts/french_1.pdf, Eds. N. Ashammakhi and P. Ferretti, 2003.
Burkhart, S.S.; ATHANASIOU, K.A.: The Twist-Lock concept of tissue transport and suture fixation without knots: Observations along the Hong Kong skyline. Arthroscopy: The Journal of Arthroscopic and Related Surgery, 19(6):613-625, 2003.
Hu, J.C.Y.; ATHANASIOU, K.A.: Structure function characteristics of articular cartilage, Chapter in Handbook of histology methods for bone and cartilage, Eds. Yuehuey H. An and Kylie L. Martin, Totowa, New Jersey, Humana Press, pp. 73-95, 2003.
Hu, J.C.Y.; ATHANASIOU, K.A.: The role of mechanical forces in tissue engineering of articular cartilage, Functional tissue engineering, Eds. F. Guilak et al., 2003
2002
Shieh, A.; ATHANASIOU, K.A.: Biomechanics of single chondrocytes and osteoarthritis, Critical Reviews in Biomedical Engineering, 30(4-6):307-343, 2002.
Hoben, G.; Huang, W.; Thoma, B.; LeBaron, R.G.; ATHANASIOU, K.A.: Quantification of varying adhesion levels in chondrocytes using the cytodetacher. Annals of Biomedical Engineering, 30:703-712, 2002.
Sweigart, M.A.; ATHANASIOU, K.A.: Biodegradable scaffolds for meniscus tissue engineering. Chapter in Tissue Engineering and Biodegradable Equivalents: Scientific and Clinical Applications. Eds. KU Lewandrowski, DL Wise, DJ Trantolo, JD Gresser, MJ Yaszemski, and DE Altobelli, New York, Marcel Dekker, pp. 225-236, 2002.
Van der Meulen, M.C.H.; Beaupre, G.S.; Smith, R.L.; Giddings, V.L.; Allen, W.A.; ATHANASIOU, K.A.; Zhu. C.F.; Mandell, J.A.; Song, Y.; Poser, R.C.; Goodman, S.B.: Factors influencing changes in articular cartilage following hip hemiarthroplasty in sheep. Journal of Orthopaedic Research, 20:669–675, 2002.
Temenoff, J.S., ATHANASIOU, K.A.; LeBaron, R.G.; Mikos, A.G.: Effect of poly(ethylene glycol) molecular weight on tensile and swelling properties of oligo(poly(ethylene glycol) fumarate) hydrogels for cartilage tissue engineering. Journal of Biomedical Materials Research, 59:429-437, 2002.
2001
Noone, T.J.; Millis, D.L.; Korvick, D.L.; ATHANASIOU, K.A.; Cook, J.L.; Kuroki, K.; Buonomo, F: Influence of canine recombinant somatotropin hormone on the biomechanical and biochemical properties of the medial meniscus in stifles with altered stability. American Journal of Veterinary Research, 63(3):419-426, 2001.
Sweigart, M.; ATHANASIOU, K.A.: Toward tissue engineering of the knee meniscus, Tissue Engineering, 7(2):111-129, 2001.
Burkhart, S.S.; Danaceau, S.M.; ATHANASIOU, K.A.: Turbulence control as a factor in improving visualization during subacromial shoulder arthroscopy. Arthroscopy: The Journal of Arthroscopic and Related Surgery, 17(2):209-212, 2001.
ATHANASIOU, K.A.; Shah, A.R., Hernandez, J.; LeBaron, R,G.: Basic science of articular cartilage repair, in Osteochondral Injuries, Clinics in Sports Medicine, Ed Robert C. Schenck, Jr., 20(2):223-247, 2001
2000
Wang, X.; Athanasiou, K.A.; Agrawal, C.M.: Fracture toughness tests of the bone-implant interface. In Mechanical Testing of Bone and the Bone-Implant Interface, Eds. Yuehuei H. An and Robert A. Draughn, CRC Press, Boca Raton, FL, 2000
ATHANASIOU, K.A.; Zhu, C-F.; Lanctot, D.R.; Agrawal, C.M.; Wang, X.: Fundamentals of biomechanics in tissue engineering of bone, Tissue Engineering, 6(4):361-381, 2000.
LeBaron, R.G.; ATHANASIOU, K.A.: Extracellular matrix cell adhesion peptides: Functional applications in orthopaedic materials, Tissue Engineering, 6(2):85-103, 2000.
ATHANASIOU, K.A.; Zhu, C.F.; Wang, X.; Agrawal, C.M.: Effects of aging and dietary restriction on the structural integrity of rat articular cartilage. Annals of Biomedical Engineering, 28(2):143-149, 2000.
LeBaron, R.G.; ATHANASIOU, K.A.: Ex vivo synthesis of articular cartilage, Biomaterials, 21(24): 2575-2587, 2000.
Agrawal, C.M.; McKinney, J.; Lanctot, D.; ATHANASIOU, K.A.: Effects of fluid flow on the in vitro degradation kinetics of biodegradable scaffolds for tissue engineering, Biomaterials, 21(23): 2443-2452, 2000.
Burkhart, S.S.; Wirth, M.A.; Simonich, M.; Salem, D.; Lanctot, D.; ATHANASIOU, K.A.: Knot security in simple sliding knots and its relationship to rotator cuff repair: How secure must the knot be? Arthroscopy: The Journal of Arthroscopic and Related Surgery, 16(2):202-207, 2000.
Wang, X.; Bank, R.A.; teKoppele, J.M.; Hubbard, G.B.; ATHANASIOU, K.A.; Agrawal, C.M.: Effect of collagen denaturation on the toughness of bone. Clinical Orthopaedics and Related Research, 371:228-240, 2000.
Agrawal, C.M.; McKinney, J.S.; Huang, D.; ATHANASIOU, K.A.: The use of the vibrating particle technique to fabricate highly porous and permeable biodegradable scaffolds, in Synthetic bioabsorbable polymers for implants, ASTM STP 1396, CM Agrawal, JE Parr, and ST Lin Eds., American Society for testing and Materials, West Conshohocken, PA, 2000.
Kose, N.; Gunal, I.; Wang, X.; ATHANASIOU, K.A; Agrawal, C.M.; Mabrey, J.D.: Setscrew distal locking for intramedullary nails: a biomechanical study. Journal of Orthopaedic Trauma, 14(6):414-419, 2000.
1999
Murray, R.C.; Zhu, C.F.; Goodship, A.E.; Lakhani, K.H.; Agrawal, C.M.; ATHANASIOU, K.A: Exercise affects the mechanical properties and histological appearance of equine articular cartilage. Journal of Orthopaedic Research, 17(5):725-731, 1999.
ATHANASIOU, K.A.; Thoma, B.; Lanctot, D.R.; Shin, D.; Agrawal, C.M.; LeBaron, R.G.: Development of the cytodetachment technique to quantify mechanical adhesiveness of the single cell. Biomaterials, 20(23-24):2405-2415, 1999.
Shin, D. and ATHANASIOU, K.A.: Cytoindentation for obtaining cell biomechanical properties. Journal of Orthopaedic Research, 17(6): 880-890, 1999.
Schenck, R.C.; Kovach, I.S.; Agarwal, A.; Brummett, R.; Ward, R.A.; Lanctot, D.; ATHANASImcnarOU, K.A.: Cruciate injury patterns in knee hyperextension: A cadaveric model. Arthroscopy: The Journal of Arthroscopic and Related Surgery, 15(5): 489-495, 1999.
ATHANASIOU, K.A.; Fleishli, J.G.; Bosma, J.; Laughlin, T.J.; Zhu, C.F; Agrawal, C.M.; Lavery, L.A.: Effects of diabetes mellitus on the biomechanical properties of human ankle cartilage. Clinical Orthopaedics and Related Research, 368:182-189, 1999.
ATHANASIOU, K.A.; Zhu, C-F.; Lanctot, D.R.; Agrawal, C.M.; Wang, X.: Bone Engineering Fundamentals. In Portland Bone Symposium 1999 Proceedings.
Zoys, G.N.; McGanity, P.L.J.; Lanctot, D.R.; ATHANASIOU, K.A.; Heckman, J.D.: Biomechanical evaluation of fixation of posterior acetabular wall fractures. The Journal of Southern Orthopaedic Association. 8(4): 254-260, 1999.
1998
Burkhart, S.S.; Wirth, M.A.; Simonich, M.; Salem, D.; Lanctot, D.; ATHANASIOU, K.A.: Loop security as a determinant of tissue fixation security. Arthroscopy: The Journal of Arthroscopic and Related Surgery, Vol. 14(7): 773-776, 1998.
Lin, J.; Shin, D.W.; ATHANASIOU, K.A.: Experimental study of articular cartilage damage and its biomechanical properties. Chinese Journal of Experimental Surgery, Vol. 15(suppl):158-159; 1998.
ATHANASIOU, K.A.; Agrawal, C.M.; Barber, F.A.; Burkhart, S.S.: Orthopaedic applications for PLA-PGA biodegradable polymers: Current concepts. The Journal of Arthroscopic and Related Surgery, Vol. 14(7): 726-737, 1998.
Armstrong, D.G; Peters, E.J.; ATHANASIOU, K.A.; Lavery, L.A.: Is there a critical level of plantar foot pressure to identify patients at risk for neuropathic foot ulcerations? Journal of Foot and Ankle Surgery, Vol. 37(4): 303-307, 1998.
Lin, J.; Shin, D.; ATHANASIOU, K.A.: Variation of the biomechanical properties of articular cartilage with its depth from the articular surface. Chinese Journal of Orthopaedics, Vol. 18(8):488-491, 1998.
Spain, T.L.; Agrawal, C.M.; ATHANASIOU, K.A.: A new technique to extend the useful life of a biodegradable cartilage implant. Tissue Engineering, Vol. 4(4): 343-352, 1998.
Fleischli, J.G.; Laughlin, T.J.; Lavery, L.A.; Shah, B.; Lanctot, D.; Agrawal, C.M.; ATHANASIOU, K.A.: The effects of diabetes mellitus on the material properties of human metatarsal bones. Journal of Foot and Ankle Surgery, Vol. 37(3): 195-198, 1998.
ATHANASIOU, K.A.; Schmitz, J.P.; Agrawal, C.M.: The effects of porosity on in vitro degradation of PLA-PGA implants used in repair of articular cartilage. Tissue Engineering, Vol. 4(1): 53-63, 1998.
Murff, R.; Armstrong, D.G.; Lanctot, D.; Lavery, L.A.; ATHANASIOU, K.A.: How effective is manual palpation in detecting subtle temperature differences? Clinics in Podiatric Medicine and Surgery, Vol. 15(1): 151-154, 1998.
ATHANASIOU, K.A.; Liu, G.T.; Lavery, L.A.; Lanctot, D.R.; Schenck, R.C.: Biomechanical topography of human articular cartilage in the first metatarsophalangeal joint. Clinical Orthopaedics and Related Research, Vol. 348: 269-281, 1998.
Lin, J.; Foote, J.; Lanctot, D.; Korvick, D.; Mabrey, J; Agrawal, C.M.; ATHANASIOU, K.A.: Optimal bypass length of femoral cortical defect in cementless hip arthroplasty: An experimental study. Chinese Journal of Orthopaedics, Vol. 18(7):418-422, 1998.
Armstrong, D.; ATHANASIOU, K.A.: The edge effect: How and why wounds grow in size and depth. Clinics in Podiatric Medicine and Surgery, Vol. 15(1):105-108, 1998.
Murray, R.C.; DeBowes, R.M.; Gaughan, E.M.; Zhu, C.F.; ATHANASIOU, K.A.: The effects of intra-articular methylprednisolone and exercise on the mechanical properties of articular cartilage in the horse. Osteoarthritis and Cartilage. Vol. 6: 106-114, 1998.
ATHANASIOU, K.A.; Rosenwasser, M.P.; Buckwalter, J.A.; Olmstead, M.; Mow, V.C.: Biomechanical modeling of repair articular cartilage: Effects of passive motion on osteochondral defects in monkey knee joints. Tissue Engineering, Vol. 4(2):185-195, 1998.
1997
Burkhart, S.S.; Pagan, J.L.D.; Wirth, M.A.; ATHANASIOU, K.A.: Cyclic loading of anchor-based rotator cuff repairs: Confirmation of the “tension overload” phenomenon and comparison of suture anchor fixation to transosseous fixation. Arthroscopy: The Journal of Arthroscopic and Related Surgery, Vol. 13(6): 720-724, 1997.
Agrawal, C.M.; ATHANASIOU, K.A.; Heckman, J.D.: Biodegradable PLA-PGA polymers for tissue engineering in orthopaedics. Materials Science Forum, Vol. 250: 115-128, 1997.
Schmitz, J.P.; Zardeneta, G.; Agrawal, C.M.; Lee, T.; ATHANASIOU, K.A.; Milam, S.B.: Protein interactions with polylactide-polyglycolide particles and scaffolds. Tissue Engineering, Vol. 3(3): 257:266, 1997.
ATHANASIOU, K.A.; Korvick, D.; Schenck, R.C.: Biodegradable implants for the treatment of osteochondral defects in a goat model. Tissue Engineering, Vol. 3(4): 363-374, 1997.
Liu, G.T.; Lavery, L.A.; Schenck, R.C.; Lanctot, D.R.; Zhu, C.F.; ATHANASIOU, K.A.: Human articular cartilage biomechanics of the second metatarsal intermediate cuneiform joint. Journal of Foot and Ankle Surgery, Vol. 36(5): 367-374, 1997.
Agrawal, C.M.; Huang, D.; Schmitz, J.P.; ATHANASIOU, K.A.: Elevated temperature degradation of a 50:50 copolymer of PLA-PGA. Tissue Engineering. Vol. 3(4): 345-352, 1997.
Korvick, D.; ATHANASIOU, K.A.: Variations in the mechanical properties of cartilage from the canine scapulohumeral joint. American Journal of Veterinary Research. Vol. 58(9): 949-953, 1997.
Lavery, L.A.; Vela, S.A.; Ashry, H.R.; Lanctot, D.R.; ATHANASIOU, K.A.: Novel methodology to obtain salient biomechanical characteristics of insole materials. Journal of the American Podiatric Medical Association, Vol. 87(6): 266-271, 1997.
Agrawal, C.M. and ATHANASIOU, K.A.: Technique to control pH in vicinity of biodegrading PLA-PGA implants, Journal of Biomedical Materials Research (Applied Biomaterials), Vol. 38(2):105-114, 1997.
Kovach, I.S. and ATHANASIOU, K.A.: Small angle HeNe laser light scatter and the compressive modulus of articular cartilage. Journal of Orthopaedic Research, Vol. 15(3): 437-441, 1997.
Burkhart, S.S.; Johnson, T.C.; Wirth, M.A.; ATHANASIOU, K.A.: Cyclic loading of transosseous rotator cuff repairs: Tension overload as a possible cause of failure. Arthroscopy: The Journal of Arthroscopic and Related Surgery, Vol. 13(2): 172-176, 1997.
Turner, A.S.; ATHANASIOU, K.A.; Zhu, C.F.; Alvis, M.R.; Bryant, H.U.: Biomechanical effects of estrogen on articular cartilage in ovariectomized sheep. Osteoarthritis and Cartilage, Vol. 5(1): 63-69, 1997.
1996
Wilkes, R.P. and ATHANASIOU, K.A.: The intrinsic incompressibility of osteoblast-like cells. Tissue Engineering, Vol. 2(3): 167-181, 1996.
Singhal, A.R., Agrawal, C.M.; ATHANASIOU, K.A.: Salient degradation features of a 50:50 PLA/PGA scaffold for tissue engineering. Tissue Engineering, Vol. 2(3): 197-207, 1996.
Burkhart, S.S.; ATHANASIOU, K.A.; Wirth, M.A.: Margin convergence: a method of reducing strain in massive rotator cuff tears. Arthroscopy: The Journal of Arthroscopic and Related Surgery, 12(3): 335-338, 1996.
Hersh, C.K.; Williams, R.P.; Trick, L.W.; Lanctot, D.; ATHANASIOU, K.A.: Comparison of the mechanical performance of trochanteric fixation devices. Clinical Orthopaedics and Related Research, 329:317-325, 1996.
Thompson, D.E.; Agrawal, C.M.; ATHANASIOU, K.A.: The effects of dynamic compressive loading on biodegradable implants of 50-50% polylactic acid-polyglycolic acid. Tissue Engineering 2(1):61-74, 1996.
ATHANASIOU, K.A.; Niederauer, G.G.; Agrawal, C.M.: Sterilization, toxicity, biocompatibility, and clinical applications of polylactic acid/polyglycolic acid copolymers. Biomaterials 17(2):93-102, 1996.
1995
ATHANASIOU, K.A.; Niederauer, G.G.; Agrawal, C.M; Landsman, A.S.: Applications of biodegradable lactides and glycolides in podiatry. Clinics in Podiatric Medicine and Surgery W.B. Saunders, Co., 12(3):475-495, 1995.
Fisher, R.; Puhl, W.; ATHANASIOU, K.A.: Defektheilung am Gelenkknorpel des Kaninchens nach Behandlung mit dem Xenon-Chlorid-Excimer-Laser. Hefte zu der Unfallchirurg 249: 219-222, 1995
Agrawal, C.M.; Niederauer, G.G.; ATHANASIOU, K.A.: Fabrication and characterization of PLA-PGA orthopedic implants. Tissue Engineering 1(3):241-252, 1995.
Murray, R.C.; Debowes, R.M.; Gaughan, E.M.; Mosier, D.E.; ATHANASIOU, K.A.: Variations in the biomechanical properties of articular cartilage of the midcarpal joint of normal horses. Veterinary and Comparative Orthopaedics and Traumatology Vol. 8:133-140, 1995.
Agrawal, C.M.; Niederauer, G.G.; Micallef, D.; ATHANASIOU, K.A.: The use of PLA-PGA polymers in orthopaedics. In Encyclopedic Handbook of Biomaterials and Bioengineering, Ed. D. Wise et al., Marcel Dekker, Inc., pp. 1055-1089, 1995.
Higgins, K.R.; Lavery, L.A.; Ashry, H.R.; ATHANASIOU, K.A.: Structural analysis of absorbable pin and screw fixation in first metatarsal osteotomies. Journal of the American Podiatric Medical Association Vol. 85(10):528-532, 1995.
ATHANASIOU, K.A.; Agarwal, A.; Muffoletto, A.; Dzida, F. J.; Constantinides, G.; Clem, M.: Biomechanical properties of hip cartilage in experimental animal models. Clinical Orthopaedics and Related Research Vol. 316: 254-266, 1995.
ATHANASIOU, K.A.; Fischer, R.; Niederauer, G.G.; Puhl, W.: Effects of excimer laser on healing of articular cartilage in rabbits. Journal of Orthopaedic Research Vol. 13(4):483-494, 1995.
ATHANASIOU, K.A.; Niederauer, G.G.; Schenck, R.C.: Biomechanical topography of human ankle cartilage. Annals of Biomedical Engineering Vol. 23(5):697-704, 1995.
ATHANASIOU, K.A.; Singhal, A.R.; Agrawal, C.M.; Boyan, B.D.: In vitro degradation and release characteristics of biodegradable implants containing trypsin inhibitor. Clinical Orthopaedics and Related Research Vol. 315: 272-281, 1995.
1994
Lavery, L.; Higgins, K.; Ashry, H.; ATHANASIOU, K.A.: Mechanical characteristics of poly-l-lactic acid absorbable screws and stainless steel screws in basilar osteotomies of the first metatarsal. Journal of Foot and Ankle Surgery Vol. 33(3):249-254, 1994.
ATHANASIOU, K.A.: Current concepts in orthopaedic biomechanics. Book Proceedings, International Conference on Medical Physics and Biomedical Engineering, Vol. 2:336-340, 1994.
ATHANASIOU, K.A.: A biomechanical analysis of articular cartilage in the human hip. Book Proceedings, International Conference on Medical Physics and Biomedical Engineering, Vol. 2:384-388, 1994.
Schenck, R.C.; ATHANASIOU, K.A.; Constantinides, G.; Gomez, E.: A biomechanical analysis of articular cartilage of human elbow and a potential relationship to osteochondritis dissecans. Clinical Orthopaedics and Related Research Vol. 299:305-312, 1994.
Haskin, C.; Cameron, I.; ATHANASIOU, K.A.: Physiological levels of hydrostatic pressure alter morphology and organization of cytoskeletal and adhesion proteins in MG-63 osteosarcoma cells. Biochemistry and Cell Biology Vol. 71:27-35, 1993.
ATHANASIOU, K.A.; Agarwal, A.; Dzida, F.J.: Comparative study of the intrinsic mechanical properties of human acetabular and femoral head cartilage. Journal of Orthopaedic Research, Vol. 12(3):340-349, 1994.
1993
Haskin, C.L.; ATHANASIOU, K.A.; Klebe, R.J.; Cameron, I.L.: A heat-shock-like response with cytoskeletal disruption occurs following hydrostatic pressure in MG-63 osteosarcoma cells. Biochemistry and Cell Biology Vol. 71:361-371, 1993.
Lavery, L.; Higgins, K.; Ashry, H.; ATHANASIOU, K.A.: Stability of absorbable fixation in basilar first metatarsal osteotomies. Journal of the American Podiatric Medical Association Vol. 83(10):557-562, 1993.
1991
ATHANASIOU, K.A.; Rosenwasser, M.P.; Buckwalter, J.A.; Malinin, T.I.; Mow, V.C.: Interspecies comparisons of in situ intrinsic mechanical properties of distal femoral cartilage. Journal of Orthopaedic Research 9(3):330-340, 1991.
1989
Mow, V.C.; Gibbs, M.C.; Lai, W.M.; Zhu, W.B.; ATHANASIOU, K.A.: Biphasic indentation of articular cartilage: II A numerical algorithm and an experimental study. Journal of Biomechanics 22(8/9):853-861, 1989.
1987
Farcy, J.P.; Weidenbaum, M.; Michelsen, C.B.; Hoeltzel, D.A.; ATHANASIOU, K.A.: A comparative biomechanical study of spinal fixation using Cotrel-Dubousset instrumentation. Spine 12:877-881, 1987.
